Jan 20, · A hereditary predisposition to breast cancer significantly influences screening and follow-up recommendations for high-risk women. However, in patients with a suggestive personal and/or family history, a specific predisposing gene is identified in Cited by: When it comes to breast cancer risk, the most important inherited gene changes are in the BRCA1 and BRCA2 genes. Women (and men) with one of these gene changes are said to have Hereditary Breast and Ovarian Cancer (HBOC) syndrome.
Breast Cancer Genetics Everyone has genes that pass along hereditary information from generation to generation. Sometimes changes occur in the gene code, and these changes are called mutations. Learn how gene mutations can affect breast cancer risk, as well as about how genetic testing works. Tests for inherited genetic mutations can provide women diagnosed with ovarian or breast cancer with important information that can have implications for family members and potentially guide treatment decisions and longer-term screening for second cancers.
Breast ultrasounds and breast MRIs can be used to screen women who are at high risk for breast cancer, usually due to a strong family history of breast cancer or a certain genetic mutation. Breast ultrasounds and breast MRIs can also be used to help diagnose breast cancer by providing more information about an area in the breast that is. Of course, knowing about an inherited genetic mutation, such as an error in the BRCA1 or BRCA2 genes that raises the risk for breast, ovarian and other cancers, can be lifesaving for someone who takes recommended preventive measures from surveillance to medication to surgery.